decumbens (R.Br.) Recommended where the mind, traumatic. raised in systolic and diastolic blood pressure was induced in rats by i.p. All Rights Reserved. of family Convolvulaceae which is available in Indian herb and spices market with the name of Shankhpushpi, widely used in the traditional system of medicine including Unani medicine since ages. Results: Both the test as well as the control drug had an extremely significant effect on the systolic blood pressure (p<0.001) while in diastolic blood pressure, control drug proved more effective (p<0.001) than test drug (p<0.01) comparatively. Objective: To evaluate antihypertensive effects of methanolic extract of Evolvulus alsinoides herb (MEEA) in adrenaline induced hypertensive rats. The work was also emphasized in determining the minimum fungicidal concentration of each plant extracts against Malassezia sp. The results obtained in the above study suggesting that, the aqueous extract of Convolvulus pluricaulis posses significant hepatoprotective activity. Gupta P, Akanksha, Siripurapu KB, Ahmad A. drug. To explore the anti-hyperlipidemic and anti-tumor effect of ethanolic extract of Evolvulus alsinoides, its chloroform fraction and isolated components in Triton-induced hyperlipidemic rats. 1528, 1808, K. 8. Dwarf morning-glory, Evolvulus alsinoides Linn., Mao la hua - Herbal Medicine - An illustrated compilation of Philippine medicinal plants by Dr Godofredo Umali Stuart of Philippine medicinal plants with botanical information, chemical properties, folkloric uses and medicinal research studies. Evolvulus alsinoides Linn. Chin J Integr Med 2014. as immunomodulatory agents. (EA)] was carried out to characterize the drug sample and set a standard of its quality. (Family-Papilionaceae) and Evolvulus alsinoides Linn. and is a perennial herb with a small woody branched rootstock; membranous, more than 30 cm long, prostrate, spreading, slender. Whatever may be the source, the drug finds use for its therapeutic effect on brain disorders like insanity, epilepsy, nervous debility and for memory enhancement 1 . Talkad*3 1CMJ University, Shillong. Fagopyrum tataricum Gaertn. All the patients in the test group were given with the test drug 3 g powder of Sankhaholi twice a day for 6 weeks orally. LF01909500 - Evolvulus alsinoides Linn., extract - Searchable synonyms, formulas, resource links, and other chemical information. Evolvulus alsinoides L.: Bioactivity guided purification of n-BuoH solube fraction from two new compounds, 2,3,4-trihydroxy3methylbutyl 3-2 propeonate and 1,3-di-O-caffeoyl quinic acid methyl ester along with 6 known compounds, caffeic acid, 6-methoxy-7-O-beta-glucopyranoside coumarine, 2-C-methyl erythritol, kaemferol-7-O-beta-glucopyranoside.The structure of new compounds were … Peduncles are very long, filiform, axillary, calyx densely silky. Conclusion: The test drug Sankhaholi (Evolvulus alsinoides Linn.) (EA) (Convulvulaceae) is also used as shankhpushpi by some practitioners. / Amritpal Singh / Ethnobotanical Leaflets 12: 734-40. Infusions of roots, stalks and leaves are all used in Nigeria as stomachics (2).In Kenya (Kwale Province) sores are treated by application of the powdered leaves (8), and in Tanganyika (Lake Province) the pounded leaves are put onto enlarged glands in the neck (13). 12. Pharmacol Biochem Behav 2005;81(3):424-32. Linn. Item Type: Specimen Genus: Evolvulus. The plant is used by certain ethnic races across India, Africa and Philippines to cure fever, cough and cold, venereal diseases, azoospermia, adenitis, and depression. [EA]) of family Convolvulaceae which is commonly known as Shankhpushpi, in the traditional system of medicine including Unani medicine. flower Agri-horticulture: ornamental, cultivated or partially tended Agri-horticulture: fodder Social: religion, superstitions, magic Social: sayings, aphorisms. (EA, family- Convulvulaceae) are used as shankhpushpi . The acute oral toxicity study was conducted as per OECD guidelines 420 and the extract was proved to be safe up to the dose of 2000 mg/kg. Exacum bicolor Roxb. Material and Method: Present clinical study was carried out to evaluate the efficacy and safety of Sankhaholi ( Evolvulus alsinoides Linn.) Farsetia hamiltonii Royle. Persistent HTN is one of the risk factors for strokes. A little deviation from the normal in terms of quality and quantity of the constituents may alter the effect of a drug. Evolvulus alsinoides L. (Convolvulaceae) is used as nootropic or brain-tonic in traditional systems of medicine like Ayurveda and Unani. The whole plant is used as brain tonic. Yadav MK, Singh SK, Singh M, Mishra SS, Singh AK, Tripathi JS, Tripathi YB. prepared with various fra ctions of Evolvulus alsinoides ; conducted acute toxicity study on mices to identifying of LD50 value. Convolvulus alsinoides L. Family Convolvulaceae. It also contains a yellow neutral fat, an organic acid, and saline substances. Cools The Body. The Sankhaholi (Evolvulus alsinoides Linn. Linn. and grassy places throughout India and other sub-tropical countries. J Ethnopharmacol 2008; 22:713. References:1. is one of the widely prescribed medicines for the management of essential hypertension in Unani medicine. Ainslie, 1937: sp. 15. Evolvulus alsinoides (Linn.) 2019Apr.11 [cited 2020Nov.13];7(7):1059-66. Department of Pharmaceutical Sciences, Dr Hari Singh Gour Vishwavidyalaya, Sagar, India. in amritsar India. It occurs in mostly dry tropical and sub-tropical regions of the world. (Fam. INTRODUCTION: Essential hypertension is a heterogeneous idiopathic disorder which accounts for about 90 to 95% of all cases of HTN 1. Fagopyrum esculentum Moench. By using various fractions to conducted Hepatoprotective activity by paracetamol induced method. The, bronchitis and asthma. In the Ayurvedic system of medicine, the whole herb of 'Shankhpushpi' has been employed clinically for centuries for its memory potentiating, anxiolytic and … INTRODUCTION Standardization is a system that ensures a predefined amount of therapeutic effect, quantity and quality of the herbal drugs and now it is considered a prerequisite for the assessment of biological activity of the plant materials. It is used in the Philippines for certain bowel irregularities (11). A single blind, placebo controlled study was conducted to evaluate the efficacy of Sankhaholi in 60 patients of Anxiety neurosis, belonging to 18-50 yrs of age group of both sexes.  The authentication of herbal drugs and identification of adulterants from genuine medicinal herbs are essential for both pharmaceutical companies as well as public health and to ensure reproducible quality of herbal medicine. The drug Sankhaholi (Evolvulus alsinoides Linn.) Department of Pharmaceutical Sciences, Dr Hari Singh Gour Vishwavidyalaya, Sagar, India. (Evolvulus alsinoides Linn.) 6. (E. alsinoides) (Convulvulaceae) is commonly known as Shankhpushpi and used in traditional medicine for antimalarial treatment by several ethnic populations of India  . Hypertension like condition i.e. The present investigation dealt with study of the potentiality of Evolvulus alsinoides, Lawsonia inermis, Hibiscus rosa-sinensis, Azadirachta indica and Murraya koenigii against Malassezia furfur. Chem Pharm Bull (Tokyo) 2007;55:771-5. shankhpushpi four verities. 155. Therapeutic uses of Sankhaholi EA, mentioned in the Unani medicine are alexiteric (Mufarreh), cardiac tonic (Muqawwi-e Qalb), brain tonic (Muqawwi-e Dimag), digestive (Hazim) Musaffi-e-Khoon (blood purifier), general tonic (Muqawwi-e-am), diuretic (Mudirr-e-Baul), anti-inflammatory (Muhallil-e-waram), hypoglycemic (Dafa-e-Ziabitus), and antihypertensive (Dafye Imtella). Preventive group animals were injected daily with the extract and stigmast-5-en-3β-ol at dose of 50 mg/kg body weight i.p. Newly diagnosed 41 patients of Essential Hypertension (22 patients were in the test group and 19 patients in the control group) were enrolled for the study. Corresponding Author. Evolvulus alsinoides var. Sheet data. In the present paper, sankhaholi was subjected to physico-chemical and chromatographic analysis to ensure the quality of herb, available in Indian market. JSTOR is part of ITHAKA, a not-for-profit organization helping the academic community use digital technologies to preserve the scholarly record and to advance research and teaching in sustainable ways. It has been predicted that by the year 2020, there will be an increase by almost 75% in the global cardiovascular disease burden because of hypertension. India. It is a perennial herb with a small woody branched rootstock which contains alkaloids: shankhapushpine and evolvine. from India Patients in the control group were given standard drug Ramipril 5 mg once a day for the same duration. Capsules are glabrous, rounded while seeds onlong and dark brown. Linn. Exogonium purga Benth. Wholesale Suppliers & Retailer of Shankhpushpi(evolvulus Alsinoides Linn.) debilis (Kunth) Ooststr. Alkaloids of Convolvulus subhirsutus from Uzbekistan. Many formulations Ethnomed Source. Whatever may be the source, the drug Þ nds use for its therapeutic effect on brain disorders like insanity, epilepsy, nervous debility and for memory enhancement1. The drug sankhaholi (EA) of family Convolvulaceae which is commonly known as shankhpushpi, in the traditional system of medicine including Unani medicine. Proceedings, DPhG Jahrestagung – Joint Meeting, Marburg, German. Evolvulus alsinoides L. (Convolvulaceae) is used as nootropic or brain-tonic in traditional systems of medicine like Ayurveda and Unani. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria. In Ayurveda, the plant Evaluation of Evolvulus alsinoides Linn… The plant is sold in N Nigeria principally as a charm worn as a girdle or circlet on the arm, etc., to procure love or a favour. EFFICACY OF SANKHAHOLI (EVOLVULUS ALSINOIDES LINN.) Council of Scientific and Industrial Research; 1992. p. 233-4. Conclusion: The finding of the study revealed that the test drug Sankhaholi (Evolvulus alsinoides Linn.) ©2000-2020 ITHAKA. (EA, family- Convulvulaceae) are used as shankhpushpi . is one of the widely prescribed medicines for the management of essential hypertension in Unani medicine. forms, plants have been utilized as therapeutic agents since old age. Evolvulus alsinoides Linn. Hepatotoxicity was induced in the animals of all groups except normal control by single dose administration of thioacetamide (100 mg/kg) at first day of the study followed by animals were treated daily with standard drug sylimarine and aqueous extract of Convovulus pluricaulis (200 mg/kg, 400 mg/kg and 600 mg/kg) to respective groups for 21 days. Farsetia jacquemontii Hook. Also, significant effect on the systolic blood pressure (p<0.001) were recorded in test group. 22. It is grazed by all stock (Senegal, 1; Sudan, 3; Kenya, 7). Therefore, to revalidate the Ayurvedic therapeutic claims of Shankhapushpi in light of contemporary experimental and clinical studies, this study was carried out. The purpose of this research work is to study the anticonvulsant activity of Evolvulus aisinoides Linn (convolvulacea) used in traditional medicine for the treatment of neurodegenerative diseases, amnesia, mental illness and epilepsy. Ayushvedah provides all the informations about sankhapushpi - Evolvulus alsinoides Linn., Convolvulus pluricaulis Chois. With the above biochemical parameters toxic group of Parac e tamol showed the elevated levels of SGPT, SGOT, ALP, CHOL and TBL where as decreased TP and ALB levels when compared with the c ontr ol group. (Family-Papilionaceae) and Evolvulus alsinoides Linn. and Evolvulus alsinoides Linn. 3. Stigmast-5-en-3β-ol showed a marked antihyperlipidemic potential by reducing the total cholesterol, triglycerides, low density lipoproteins level, and significantly increased high density lipoprotein level compared with other isolated component. It is grazed by all stock (Senegal, 1; Sudan, 3; Kenya, 7). 36. Access is allocated within two business days of purchase and lasts one year. Tanner 1420, K. 13. But in the animals treated with aqueous extract and standard drug silymarine, all the parameters were normal possibly due to their beneficial property in protecting the liver against thioacetamde induced hepatotoxicity. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria. Convolvulaceae) is a diffuse, densely hispid, perennial herb with a woody branched root-stock and many spreading branches found wild in most parts of India in the plains and other tropical and subtropical countries . oil. Evolvulus nummularius Linn. Irvine 283, K. 10. Linn. Evolvulus alsinoides Linn. Item Type: Specimen Family Convolvulaceae. Getahun, 1975. Objective: To study the anthelmintic and antimicrobial activities of the ethanolic extract of Evolvulus alsinoides Linn. In view of these facts, physico-chemical standardization of sankhaholi [Evolvulus alsinoides Linn. Since it is an essential ingredient of myriad popular Ayurvedic monoherbal or polyherbal preparations, it is commercially quite exploitable. Linn. In the current research, enzyme inhibition and cytotoxic potentials of E. alsinoides (L.) L. leaf extract has been studied validating its potential application. 15. administration of adrenaline (0.5 mg/kg/100 μL). no. Linn. The presence of these phytochemicals is an indicator that the plant can be a potential source of precursors in the development of synthetic drugs. 3. ternatea Linn. on paracetamol induced rats. Essential hypertension (HTN) is the most prevalent type of HTN, affecting 90 to 95% of hypertensive patients. The plant is used by certain ethnic races across India, Africa and Philippines to cure fever, cough and cold, venereal diseases, azoospermia, adenitis, and depression. Item Type: Specimen Family Convolvulaceae. Joshi UH, Ganatra TH, Desai TR, Tirgar PR. Context: Evolvulus alsinoides Linn. EXPLORE UNANI MANAGEMENT FOR LIFESTYLE DISORDERS, Sankhaholi (Evolvulus alsinoides Linn.) The severity of anxiety symptoms was assessed by Hamilton's Anxiety Rating Scale (HARS), which was administered at baseline, at every week for 4 weeks, and then at 6th week of treatment (the treatment end point). is safe and has substantial efficacy as an antihypertensive drug. on learning behavior and memory enhancement activity in rodents. Irvine, 1930: 192–3. Evolvulus alsinoides Linn. ternatea Linn. Newly diagnosed 41 patients of Essential Hypertension (22 patients were in the test group and 19 patients in the control group) were enrolled and their clinical, as well as hematological parameters, were recorded at baseline, 21 st day and 42 nd day. It also contains a yellow neutral fat, an organic acid, and saline substances. Material and Methods: The present clinical study was carried out to evaluate the safety of Sankhaholi (Evolvulus alsinoides Linn.) leaves In Vitro Antioxidant Activity of Extracts from Fruits of Muntingia calabura Linn. Review of Ethnomedicinal Uses and Pharmacology of Evolvulus alsinoides Linn. Quisumbing, 1951: 756–7. The current work appears to be the first of its kind and can be considered a reference standard for future studies. and Evolvulus alsinoides Linn. Evolvulus alsinoides Linn. Anti Bacterial and Anti Oxidant Activities of Evolvulus Alsinoides Linn Nazanin Soudbakhsh Moghadam1, Anil Kumar H.V 2, Laksmikanth. Item Type: Specimen Genus: Evolvulus. [EA]) of family Convolvulaceae which is commonly known as Shankhpushpi, in the traditional system of medicine including Unani medicine. Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice. Fresh plant of sankhaholi contains volatile, Background: Hypertension is one of the major risk factors for stroke, heart attack, heart failure, and kidney failure, thereby cause of deaths and disability worldwide. Effect of Evolvulus alsinoides Linn. Leaves are small numerous 6-20 by 4-8 mm, alternate, elliptic-oblong, obtuse, strongly petioles v, pairs.